Influence of the sodium hypochlorite on the healing process of the dog’s teeth treated in single-visit

Mauro Juvenal Nery, João Eduardo Gomes-Filho, Roberto Holland, Valdir de Souza, Pedro Felício Estrada Bernabé, José Arlindo Otoboni Filho, Elói Dezan Júnior, Luciano Tavares Angelo Cintra, Carolina Simonetti Lodi

Introduction: Elimination of bacteria from root canals is essential in the endodontic treatment of necrotic pulp teeth once bacteria not only cause, but also maintain, periapical lesions. Objective: The aim of this study was to analyze, in vivo, the influence of the irrigating solutions (1.0% NaOCl, 2.5% NaOCl, 0.9% sterile saline) in single visit treatment of dogs’ teeth with chronic periapical lesion. Methods: Forty root canals from three Beagle dogs were left exposed to the oral cavity to allow contamination and formation of the chronic periapical lesion. After that, the root canals were biomechanically prepared. During the instrumentation, three irrigating solutions were used: G1- 2.5% NaOCl; G2-1.0% NaOCl; G3-0.9% sterile saline. Control Group (G4) had no treatment and no coronal sealing. The root canals were filled with gutta-percha points and Sealapex. The crown openings were sealed with IRM® and amalgam. After six months, the animals were sacrificed and blocks of tissue histologically processed to be stained with hematoxylin and eosin, or Brown and Brenn. Results: There was no histological difference between the utilization of 1.0% or 2.5% sodium hypochlorite (p>0.05), but between them and sterile saline (p<0.05). Conclusion: It was concluded that the use of irrigating solutions with antibacterial potential (1% or 2.5% sodium hypochlorite) provided more favorable conditions for the healing process.

Keywords: Root canal treatment. Irrigating solution. Sodium hypochlorite. Biocompatibility. Healing process.

How to cite: Nery MJ, Gomes-Filho JE, Holland R, Souza V, Bernabé PFE, Otoboni Filho JA, Dezan Júnior E, Cintra LTA, Lodi CS. Inluence of the sodium hypochlorite on the healing process of the dog’s teeth treated in single-visit. Dental Press Endod. 2011 July-Sept;1(2):21-7.

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