Efficiency of different concentrations of sodium hypochlorite during endodontic treatment. Literature review

Jefferson J. C. Marion, Frederico Campos Manhães, Homero Bajo, Thaís Mageste Duque

The aim of this study is to evaluate, through a literature review, the effectiveness of various concentrations of sodium hypochlorite during endodontic treatment. It was possible to verify that the 0.5% sodium hypochlorite concentration needs more time to dissolve organic tissue while causing less irritation to periapical tissues. The 1% concentration showed lower loss of chlorine due to the presence of stabilizer, making the solution more reliable for long periods after open. The 2.5% concentration showed better bactericidal action and a good tissue dissolution time; the 5.25% concentration showed higher solvent potential and bactericidal effect, with lower surface tension and consequently better root canal decontamination. However, the highest concentration was also more toxic to periapical tissues, promoting greater irritation. Based on the literature review it can be said that the 2.5% sodium hypochlorite concentration, due to its less cytotoxic properties, is the most suitable for endodontic treatment of root canals.

Keywords: Sodium hypochlorite. Antimicrobial activity. Organic solvent. Irrigation solutions.

How to cite: Marion JJC, Manhães FC, Bajo H, Duque TM. Efficiency of different concentrations of sodium hypochlorite during endodontic treatment. Literature review. Dental Press Endod. 2012 Oct-Dec;2(4):32-7.

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