Radiographic evaluation of pulpal and periapical response of dogs teeth to Emdogain® used as pulpotomy agent

Léa Assed Bezerra SILVA, Lisa Danielly Curcino ARAUJO, Marcela Martin del Campo FIERRO, Kleber Cortês BONIFÁCIO, Renato PETILLE, Francisco Wanderley Garcia PAULA SILVA

Introduction: The enamel matrix derivative (Emdogain®) is a protein extract used for periodontal healing. The objective of this study was to evaluate radiographically the pulpal and periapical response of dogs teeth after pulpotomy and use of enamel matrix derivative gel (Emdogain®). Methods: Pulpotomy was performed in 30 teeth (60 roots) from 3 dogs and the remaining pulp tissue was capped with the following materials: Groups 1 and 4: enamel matrix derivative gel (Emdogain®); Groups 2 and 5: calcium hydroxide; Groups 3 and 6: zinc oxide and eugenol cement. After 10 days (Groups 1-3) and 75 days (Groups 4-6) periapical radiographs were obtained and the radiographic evaluation was performed considering the integrity of the lamina dura, presence of areas of periapical bone rarefaction, root resorption (internal and external) and dentin bridge formation. Results: In the 10- day period, all specimens in Groups 1-3 presented absence of periapical bone rarefaction, absence of root resorption (internal and external) and absence of dentin bridge formation. In the 75-day period, Groups 4-6 did not present dentin bridge formation in any specimen. Periapical bone rarefaction areas were observed in 100% of the roots in Group 4, 62,5% of the roots in Group 6 and in 25% of the roots in Groups 5. Conclusion: The use of enamel matrix derivative gel (Emdogain®) as a capping material after pulpotomy lead to formation of periapical lesions and did not induce deposition of mineralized tissue.

Keywords: Pulpotomy. Calcium Hydroxide. Zinc OxideEugenol Cement. Dental Enamel Proteins

How to cite: Silva LAB, Araujo LDC, Fierro MMC, Bonifácio KC, Petille R, Paula-Silva FWG. Radiographic evaluation of pulpal and periapical response of dogs teeth to Emdogain® used as pulpotomy agent. Dental Press Endod. 2021 Jan-Apr;11(1):29-34.

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