Histopathological evaluation of the influence of root canal obturation in the repair of apical periodontitis in animals: a systematic review

Marcos Vinicius COOK, Alena Ribeiro Alves Peixoto MEDRADO, Ronaldo Araújo SOUZA

Introduction: Root canal fillings are a decisive factor in the success of endodontic treatment. This systematic review evaluated animal studies using histopathological parameters to determine the effect of root canal filling on the healing of apical periodontitis. Methods: A search was conducted in PubMed, Lilacs, Scielo, Science Direct and BBO using indexed and non-indexed keywords. Studies published from 2003 to 2019 were selected according to inclusion and exclusion criteria. Results: Five animal studies met eligibility criteria and were included in the systematic review for a qualitative analysis. Conclusion: The extension of the root canal filling may affect the healing of apical periodontitis when bacteria remain in the canal. Root canal sealers with antimicrobial properties were not effective in eliminating bacteria remaining in the root canal, nor in promoting the complete healing of apical periodontitis.

Keywords: Obturação do canal radicular. Periodontite periapical. Cicatrização.

How to cite: Cook MV, Medrado ARAP, Souza RA. Histopathological evaluation of the influence of root canal obturation in the repair of apical periodontitis in animals: a systematic review. Dental Press Endod. 2021 Jan-Apr;11(1):84-91.

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