Genetic analysis of craniofacial problems – a review of the literature and some guidelines for clinical and laboratorial investigation (part 1)

Ricardo Machado CRUZ, Silviene Fabiana de OLIVEIRA

Introduction: New researches show the important role played by genes in the etiology of craniofacial problems. In spite of that, knowledge of the basis of Human Genetics is still very far from the daily practice of clinical dentists. Aim: The main aim of this paper is to serve as a valuable source of information on Genetics for readers, supplying them with the main concepts and nomenclature in this field. Methods: The authors provide an overview of central concepts and topical issues in modern genetic investigation, with special attention to the complex and multifactorial disorders that disturb the normal process of craniofacial growth and development. Results and Conclusion: It is indispensable for updated clinical dentists to have at least a basic knowledge about the basis of Human Genetics in order to follow its current and future progresses in both areas: clinical investigative and Molecular Genetics.

Keywords: Human Genetics. Genetic analysis. Craniofacial growth and development.

Saturday, December 28, 2024 22:36