Clinical and radiographic evaluation of phenobarbital (Gardenal®) influence on orthodontic movement: a study in rabbits

Matheus Melo PITHON, Antônio Carlos de Oliveira RUELLAS

The objective of the present study was to evaluate the clinical and radiographic phenobarbital influence on orthodontic movement. 22 New Zealand rabbits (Oryctolagus cuniculus) have been used for study, all divided into three groups: N = normal rabbits; C = control rabbits; and E = experimental rabbits. No procedure was performed in Group N (n = 2), except a certification of the normal condition. In Groups C (n = 10) and E (n = 10), orthodontic device was placed between the lower first molars and the lower incisors in order to promote a mesial molar movement. In Group E, phenobarbital was administered together the treatment. Following the periods of 7 and 14 days, the animals were sacrificed for clinical and radiographic analysis. By comparing the control animals with the experimental ones, the results showed no difference on the rate of orthodontic tooth moment as well no radiographic change.

Keywords: Tooth movement. Drug. Orthodontic.

Wednesday, November 27, 2024 01:22